yap1 protein (Oryzias latipes) - STRING interaction network

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yap1

Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. (440 aa)

Predicted Functional Partners:

LOC101169307

0.991

lats1

0.985

lats2

0.978

tjp2

0.973

LOC101175466

0.952

ctnnb1

0.952

LOC101155570

0.952

sav1

0.947

LOC100049312

0.946

tead4

0.935

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100049312	lats1	ENSORLP00000037477	ENSORLP00000022058	TEA domain-containing protein.	Large tumor suppressor kinase 1.	0.453
LOC100049312	lats2	ENSORLP00000037477	ENSORLP00000034697	TEA domain-containing protein.	Large tumor suppressor kinase 2.	0.453
LOC100049312	yap1	ENSORLP00000037477	ENSORLP00000003377	TEA domain-containing protein.	Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation.	0.946
LOC101155570	LOC101169307	ENSORLP00000043944	ENSORLP00000032294	Serine/threonine kinase 3 (STE20 homolog, yeast).	Angiomotin.	0.647
LOC101155570	LOC101175466	ENSORLP00000043944	ENSORLP00000024937	Serine/threonine kinase 3 (STE20 homolog, yeast).	Uncharacterized protein.	0.902
LOC101155570	lats1	ENSORLP00000043944	ENSORLP00000022058	Serine/threonine kinase 3 (STE20 homolog, yeast).	Large tumor suppressor kinase 1.	0.885
LOC101155570	lats2	ENSORLP00000043944	ENSORLP00000034697	Serine/threonine kinase 3 (STE20 homolog, yeast).	Large tumor suppressor kinase 2.	0.885
LOC101155570	sav1	ENSORLP00000043944	ENSORLP00000011283	Serine/threonine kinase 3 (STE20 homolog, yeast).	Salvador family WW domain containing protein 1.	0.972
LOC101155570	yap1	ENSORLP00000043944	ENSORLP00000003377	Serine/threonine kinase 3 (STE20 homolog, yeast).	Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation.	0.952
LOC101169307	LOC101155570	ENSORLP00000032294	ENSORLP00000043944	Angiomotin.	Serine/threonine kinase 3 (STE20 homolog, yeast).	0.647
LOC101169307	LOC101175466	ENSORLP00000032294	ENSORLP00000024937	Angiomotin.	Uncharacterized protein.	0.647
LOC101169307	ctnnb1	ENSORLP00000032294	ENSORLP00000031608	Angiomotin.	Catenin (cadherin-associated protein), beta 1.	0.639
LOC101169307	lats1	ENSORLP00000032294	ENSORLP00000022058	Angiomotin.	Large tumor suppressor kinase 1.	0.967
LOC101169307	lats2	ENSORLP00000032294	ENSORLP00000034697	Angiomotin.	Large tumor suppressor kinase 2.	0.935
LOC101169307	sav1	ENSORLP00000032294	ENSORLP00000011283	Angiomotin.	Salvador family WW domain containing protein 1.	0.960
LOC101169307	yap1	ENSORLP00000032294	ENSORLP00000003377	Angiomotin.	Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation.	0.991
LOC101175466	LOC101155570	ENSORLP00000024937	ENSORLP00000043944	Uncharacterized protein.	Serine/threonine kinase 3 (STE20 homolog, yeast).	0.902
LOC101175466	LOC101169307	ENSORLP00000024937	ENSORLP00000032294	Uncharacterized protein.	Angiomotin.	0.647
LOC101175466	lats1	ENSORLP00000024937	ENSORLP00000022058	Uncharacterized protein.	Large tumor suppressor kinase 1.	0.885
LOC101175466	lats2	ENSORLP00000024937	ENSORLP00000034697	Uncharacterized protein.	Large tumor suppressor kinase 2.	0.885

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