STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101158788Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)    
Predicted Functional Partners:
pafah1b3
Platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit.
    
 0.991
LOC101159126
Platelet-activating factor acetylhydrolase 1b, catalytic subunit 2.
    
 0.991
nudc
NudC nuclear distribution protein.
   
 0.983
pla2g7
Platelet-activating factor acetylhydrolase.
     
 0.939
ckap5
Cytoskeleton associated protein 5.
    
 0.929
LOC101158306
Dynein, cytoplasmic 1, intermediate chain 2b.
   
 0.907
DYNC1I1
Dynein cytoplasmic 1 intermediate chain 1.
   
 0.907
dync1i2
Dynein, cytoplasmic 1, intermediate chain 2a.
   
 0.907
dctn2
Dynactin 2 (p50).
   
 0.906
LOC101161012
Lysophosphatidylcholine acyltransferase 4.
     
  0.900
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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