Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC101158540RBR-type E3 ubiquitin transferase. (794 aa)    
Predicted Functional Partners:
ube2l3
Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.633
rps27a
Ribosomal protein S27a.
    
  0.615
vcp
Valosin containing protein; Belongs to the AAA ATPase family.
   
 
 0.612
LOC101158291
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.609
trip12
Thyroid hormone receptor interactor 12.
   
 
 0.573
rnf7
Ring finger protein 7.
    
 0.559
psmc3
Proteasome 26S subunit ATPase 3; Belongs to the AAA ATPase family.
     
 0.558
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.522
H2M970_ORYLA
Ubiquitin-like domain-containing protein.
    
  0.522
sod3
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
    
 
 0.515
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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