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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gtf3c3General transcription factor IIIC, polypeptide 3. (943 aa)    
Predicted Functional Partners:
gtf3c5
General transcription factor IIIC, polypeptide 5.
   
 0.999
polr3d
Polymerase (RNA) III (DNA directed) polypeptide D.
    
 0.983
LOC101173800
Myb_DNA-bind_7 domain-containing protein.
   
 0.983
gtf3c2
General transcription factor IIIC, polypeptide 2, beta.
    
 0.974
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
   
   0.972
cpsf1
Cleavage and polyadenylation specific factor 1.
    
   0.970
gtf3c4
General transcription factor IIIC, polypeptide 4.
   
 0.968
LOC101163291
BRF1 RNA polymerase III transcription initiation factor subunit.
    
 0.964
H2MVC6_ORYLA
TFIIB-type domain-containing protein.
    
 0.964
ENSORLP00000036416
TFIIB domain-containing protein.
    
 0.964
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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