Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ctnsCystinosin, lysosomal cystine transporter. (498 aa)    
Predicted Functional Partners:
shpk
Sedoheptulokinase.
      
 0.887
mfsd12
Major facilitator superfamily domain containing 12a.
      
 0.757
slc66a1
Solute carrier family 66 member 1.
   
 
 0.736
slc17a5
Solute carrier family 17 member 5.
      
 0.642
lamp1
Lysosomal associated membrane protein 1a.
      
 0.603
pi4k2a
Phosphatidylinositol 4-kinase type 2 alpha.
   
  
 0.603
pi4k2b
Phosphatidylinositol 4-kinase type 2 beta.
   
  
 0.603
sumf1
Sulfatase modifying factor 1.
      
 0.598
btg3
B-cell translocation gene 3.
      
 0.586
LOC101168467
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.585
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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