Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
appl2Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (666 aa)    
Predicted Functional Partners:
appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
   
 
 0.967
LOC101161737
Si:ch211-57n23.4.
    
 0.883
ENSORLP00000026301
Ig-like domain-containing protein.
    
 0.883
ENSORLP00000027091
Uncharacterized protein.
    
 0.883
dcc
DCC netrin 1 receptor.
    
 0.883
igdcc4
Immunoglobulin superfamily, DCC subclass, member 4.
    
 0.883
igdcc3
Immunoglobulin superfamily, DCC subclass, member 3.
    
 0.883
neo1
Neogenin 1b.
    
 0.883
LOC101174244
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.858
LOC101174851
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.858
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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