Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H2LCK0_ORYLAClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (198 aa)    
Predicted Functional Partners:
cldn11
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
     
 0.630
tjp2
Tight junction protein 2a (zona occludens 2); Belongs to the MAGUK family.
   
 
 0.534
LOC101159117
Torsin family 1.
      
 0.464
scarb1
Scavenger receptor class B, member 1; Belongs to the CD36 family.
      
 0.463
ENSORLP00000027266
Connexin 28.1.
  
  
 0.444
H2MKZ7_ORYLA
Uncharacterized protein.
  
  
 0.439
GJA9
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
  
     0.410
LOC101169804
Epithelial cell adhesion molecule.
   
 
 0.407
LOC101163673
Occludin a.
    
 
 0.404
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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