STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101174651Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (518 aa)    
Predicted Functional Partners:
cyp1a
Cytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
  
 0.970
hsd17b1
Hydroxysteroid (17-beta) dehydrogenase 1.
   
 
 0.969
3bhsd
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
   
 0.968
hsd17b3
Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.957
LOC101165994
20beta-hydroxysteroid dehydrogenase type2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.950
cyp17
Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction; Belongs to the cytochrome P450 family.
  
0.950
LOC101158433
Hydroxysteroid (17-beta) dehydrogenase 7.
    
 0.949
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
    
 0.948
cyp17a2
Cytochrome P450 family 17 polypeptide 2; Belongs to the cytochrome P450 family.
  
0.946
cyp11b
Cytochrome P450 11beta; Belongs to the cytochrome P450 family.
  
 
0.945
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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