Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mapk6Mitogen-activated protein kinase 6. (743 aa)    
Predicted Functional Partners:
mapkapk5
MAPK activated protein kinase 5.
    
 0.998
mapk4
Mitogen-activated protein kinase 4.
   
 
  0.995
neurl4
Neuralized E3 ubiquitin protein ligase 4.
    
 
 0.943
rps27a
Ribosomal protein S27a.
    
 0.821
cdc14a
Cell division cycle 14Ab.
    
 0.790
LOC101163582
Uncharacterized protein.
    
 0.790
LOC101175126
Exportin 1 (CRM1 homolog, yeast) a.
    
 0.773
LOC101169249
Non-specific serine/threonine protein kinase.
   
 0.773
pak2
Non-specific serine/threonine protein kinase.
   
 0.773
LOC101170539
Exportin 1 (CRM1 homolog, yeast) b.
    
 0.773
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.