Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (774 aa)    
Predicted Functional Partners:
LOC101159013
Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family.
    
  0.930
pik3cg
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
    
  0.930
pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
    
  0.930
pik3cd
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
  0.930
pik3r5
Phosphoinositide-3-kinase, regulatory subunit 5.
   
 
0.922
PIK3R5
Phosphoinositide-3-kinase regulatory subunit 5.
   
 
0.916
pik3r3
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
 0.849
LOC101168199
WD_REPEATS_REGION domain-containing protein.
     
  0.686
gnb5
Guanine nucleotide binding protein (G protein), beta 5a.
     
  0.686
ol-gb
WD_REPEATS_REGION domain-containing protein.
     
  0.686
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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