Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
usp8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1078 aa)    
Predicted Functional Partners:
stam2
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2.
    
 0.992
stam
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1.
    
 0.977
ubc
Ubiquitin B.
   
 0.968
hgs
Hepatocyte growth factor-regulated tyrosine kinase substrate.
   
 0.952
rnf41
Ring finger protein 41.
    
 0.948
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.937
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.934
birc6
Baculoviral IAP repeat containing 6.
   
 0.932
LOC101165394
GRB2 related adaptor protein 2a.
    
 
 0.906
rps27a
Ribosomal protein S27a.
    
 0.867
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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