Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
hdcHistidine decarboxylase. (659 aa)    
Predicted Functional Partners:
hal
Histidine ammonia-lyase; Belongs to the PAL/histidase family.
     
 0.936
LOC101174335
Histamine N-methyltransferase.
     
 0.927
LOC101158841
Histamine N-methyltransferase.
     
 0.927
aoc1
Amine oxidase.
     
 0.921
cndp2
Carnosine dipeptidase 2.
   
 
 0.918
dbh
Dopamine beta-hydroxylase (dopamine beta-monooxygenase).
     
 0.814
tph1
Uncharacterized protein.
   
 0.798
th
Tyrosine hydroxylase 1.
   
 0.681
hcrtr2
Hypocretin (orexin) receptor 2.
      
 0.661
aanat2
Arylalkylamine N-acetyltransferase 2.
     
 0.632
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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