STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sqleSqualene epoxidase a. (572 aa)    
Predicted Functional Partners:
fdft1
Farnesyl-diphosphate farnesyltransferase 1.
  
 
 0.998
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 
 0.996
H2N0C8_ORYLA
Cytochrome P450, family 51; Belongs to the cytochrome P450 family.
  
 0.987
hmgcs1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.984
nsdhl
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
   
 
 0.974
sigmar1
Sigma non-opioid intracellular receptor 1.
   
 
 0.970
dhcr7
7-dehydrocholesterol reductase.
   
 
 0.961
msmo1
Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.
   
 
 0.949
LOC100125499
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
  
 0.946
ch25h
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 
 0.938
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.