Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ptprfProtein tyrosine phosphatase receptor type Fa. (1802 aa)    
Predicted Functional Partners:
lrrc4b
Leucine rich repeat containing 4Ba.
    
 0.958
LOC101159140
Leucine rich repeat containing 4Bb.
    
 0.958
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 0.952
LOC101168764
Tyrosine-protein kinase receptor.
    
  0.941
LOC101166254
Tyrosine-protein kinase receptor.
    
  0.941
LOC101171502
Uncharacterized protein.
   
  0.920
LOC101165750
Si:ch211-284e13.4.
    
  0.903
irs2
Insulin receptor substrate 2b.
    
  0.903
LOC101163034
Si:ch73-335l21.1.
    
  0.903
LOC101174984
Insulin receptor substrate 2a.
    
  0.903
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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