Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
usp43Ubiquitin specific peptidase 43a; Belongs to the peptidase C19 family. (1216 aa)    
Predicted Functional Partners:
usp14
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.734
ubc
Ubiquitin B.
    
 0.714
trip12
Thyroid hormone receptor interactor 12.
    
 
 0.706
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.691
usp30
Ubiquitin carboxyl-terminal hydrolase.
   
 
 0.679
usp10
Ubiquitin carboxyl-terminal hydrolase.
    
 0.649
LOC101164496
Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family.
   
 0.639
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.636
rps27a
Ribosomal protein S27a.
    
 0.631
rfc4
Replication factor C (activator 1) 4.
   
 0.610
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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