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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YAF2RanBP2-type domain-containing protein. (182 aa)    
Predicted Functional Partners:
pcgf6
Polycomb group ring finger 6.
    
 0.954
RING1
Ring finger protein 1.
    
 0.948
rnf2
Ring finger protein 2.
    
 0.929
l3mbtl2
L3MBTL histone methyl-lysine binding protein 2.
    
 0.863
PCGF3
Polycomb group ring finger 3.
    
 0.862
pcgf5
Polycomb group ring finger 5a.
    
 0.848
wdr5
WD repeat domain 5.
    
 
 0.832
LOC101172867
THAP-type domain-containing protein.
   
 0.799
pcgf2
RING-type domain-containing protein.
    
 0.788
H2LSI7_ORYLA
Bmi1 polycomb ring finger oncogene 1a.
    
 0.749
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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