Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
enc1Ectodermal-neural cortex 1. (591 aa)    
Predicted Functional Partners:
LOC101172920
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.805
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.805
snx33
Sorting nexin.
      
 0.794
plagl2
Pleiomorphic adenoma gene-like 2.
    
 0.751
rag1
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]
      
 0.721
nudcd3
NudC domain containing 3.
    
   0.704
ficd
FIC domain containing.
      
 0.698
MYH6
Myosin_tail_1 domain-containing protein.
    
 
 0.688
ptchd1
Patched domain containing 1.
      
 0.675
nfe2l2
Nuclear factor, erythroid 2-like 2a.
    
  0.669
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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