Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
H2LDV5_ORYLAUncharacterized protein. (381 aa)    
Predicted Functional Partners:
plk4
Polo-like kinase 4 (Drosophila).
   
 0.995
cep63
CEP63 domain-containing protein.
   
 
 0.904
seh1l
SEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family.
 
    
 0.901
cep85
Centrosomal protein 85.
    
 
 0.896
bora
Bora aurora kinase A activator.
   
 
 0.893
aurkb
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.861
aurka
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.861
cep76
Centrosomal protein 76.
   
 
 0.854
nedd1
NEDD1 gamma-tubulin ring complex targeting factor.
   
 0.843
LOC101174063
WD_REPEATS_REGION domain-containing protein.
   
 0.843
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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