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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rreb1Ras responsive element binding protein 1a. (1807 aa)    
Predicted Functional Partners:
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
      
 0.581
kdm1a
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.572
nfe2l2
Nuclear factor, erythroid 2-like 2a.
      
 0.558
LOC101163430
Interferon regulatory factor.
    
 0.508
ambra1
Autophagy/beclin-1 regulator 1b.
    
 0.503
chd2
Chromodomain helicase DNA binding protein 2.
   
 0.442
chd1
Chromodomain helicase DNA binding protein 1.
   
 0.442
LOC105357520
IRF tryptophan pentad repeat domain-containing protein.
    
 0.406
snap23
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
    
 0.403
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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