Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
ovca2OVCA2 serine hydrolase domain containing. (223 aa)    
Predicted Functional Partners:
dph1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.
 
 
  
 0.991
tyms
Thymidylate synthetase.
     
 0.712
pigs
Phosphatidylinositol glycan anchor biosynthesis, class S.
   
   0.706
maats1
MYCBP-associated, testis expressed 1.
      
 0.691
heatr5b
HEAT repeat containing 5B.
      
 0.636
dph2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.
   
  
 0.622
suox
Sulfite oxidase.
      
 0.602
sox6b
SRY-box containing gene 6b.
      
 0.600
tmem67
Transmembrane protein 67.
      
 0.584
chordc1
Cysteine and histidine-rich domain (CHORD) containing 1b.
 
    
 0.581
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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