STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
H2LE16_ORYLAClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (275 aa)    
Predicted Functional Partners:
LOC101163673
Occludin a.
   
 
 0.503
H2M6P6_ORYLA
Claudin 23a.
   
 
 0.501
clcn3
Chloride channel protein.
      
 0.429
LOC101160233
Tight junction protein 1b; Belongs to the MAGUK family.
   
 
 0.419
LOC101166369
Tight junction protein 1a; Belongs to the MAGUK family.
   
 
 0.419
tjp2
Tight junction protein 2a (zona occludens 2); Belongs to the MAGUK family.
   
 
 0.415
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.