STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2LE16_ORYLAClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (275 aa)    
Predicted Functional Partners:
pex19
Peroxisomal biogenesis factor 19.
    
 0.464
H2M6P6_ORYLA
Claudin 23a.
   
 
 0.460
pex3
Peroxisomal biogenesis factor 3.
     
 0.453
pex13
Peroxisomal biogenesis factor 13.
     
 0.434
LOC101163673
Occludin a.
   
 
 0.429
pex12
Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.
     
 0.419
clcn3
Chloride channel protein.
      
 0.404
gdap1
Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.
    
 0.401
pex16
Peroxisomal membrane protein PEX16.
     
 0.401
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.