STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
LOC101169841Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1996 aa)    
Predicted Functional Partners:
scn2b
Sodium channel, voltage-gated, type II, beta.
   
 0.973
LOC101169720
Sodium channel, voltage-gated, type IV, beta a.
    
 0.962
LOC101159760
Ig-like domain-containing protein.
    
 0.961
LOC101162070
Sodium channel, voltage-gated, type I, beta a.
    
 0.961
scn3b
Sodium channel, voltage-gated, type III, beta.
   
 0.953
LOC101170963
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
  
 
0.925
LOC101169965
Sodium channel, voltage-gated, type IV, beta b.
    
 0.921
cacna1h
Calcium channel, voltage-dependent, T type, alpha 1H subunit b.
   
0.919
LOC101161560
Calcium channel, voltage-dependent, T type, alpha 1H subunit a.
   
0.919
cacna1a
Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b.
   
 
0.904
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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