STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101169841Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1996 aa)    
Predicted Functional Partners:
Unc79
Uncharacterized protein.
   
 0.991
scn2b
Sodium channel, voltage-gated, type II, beta.
   
 0.858
LOC101159760
Ig-like domain-containing protein.
   
 0.833
LOC101162070
Sodium channel, voltage-gated, type I, beta a.
   
 0.833
LOC101169720
Sodium channel, voltage-gated, type IV, beta a.
    
 0.799
scn3b
Sodium channel, voltage-gated, type III, beta.
   
 0.742
ENSORLP00000042482
Ion_trans domain-containing protein.
  
0.726
ENSORLP00000044666
Ion_trans domain-containing protein.
  
0.726
cacna1h
Calcium channel, voltage-dependent, T type, alpha 1H subunit b.
   
0.704
LOC101161560
Calcium channel, voltage-dependent, T type, alpha 1H subunit a.
   
0.704
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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