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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101167568Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B. (552 aa)    
Predicted Functional Partners:
DCAF7
DDB1 and CUL4 associated factor 7.
   
 
 0.913
lin52
Lin-52 DREAM MuvB core complex component.
    
 0.698
lin54
Lin-54 DREAM MuvB core complex component.
   
 0.671
RNF169
Ring finger protein 169.
   
 
 0.602
lin37
Lin-37 DREAM MuvB core complex component.
     
 0.564
lin9
Lin-9 DREAM MuvB core complex component.
    
 0.552
rbbp4
Retinoblastoma binding protein 4.
   
 0.511
LOC101156710
Retinoblastoma binding protein 4, like.
   
 0.511
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.
    
 0.505
LOC101160197
E1A binding protein p300 a.
   
 0.461
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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