Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppoxProtoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (497 aa)    
Predicted Functional Partners:
cpox
Coproporphyrinogen oxidase.
  
 
 0.999
fech
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
  
 0.999
urod
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.998
alad
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
  
 0.923
hmbs
Hydroxymethylbilane synthase a.
  
  
 0.911
uros
Uroporphyrinogen III synthase.
  
  
 0.810
alas1
5-aminolevulinate synthase.
     
 0.805
gale
UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
    
 0.794
abcb6
ATP-binding cassette, sub-family B (MDR/TAP), member 6a.
      
 0.758
ccdc32
Coiled-coil domain containing 32.
      
 0.755
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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