Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
H2LE95_ORYLADysferlin, limb girdle muscular dystrophy 2B (autosomal recessive). (1304 aa)    
Predicted Functional Partners:
ENSORLP00000038535
Uncharacterized protein.
 
     0.928
ENSORLP00000029937
Uncharacterized protein.
 
     0.927
LOC101175047
Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
      
 0.817
LOC101155291
Signal-induced proliferation-associated 1.
   
  
 0.786
anxa6
Annexin.
   
 0.655
pde6c
Phosphodiesterase.
   
  
 0.626
LOC101174851
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
  
 0.509
anxa1
Annexin.
   
 0.501
aplp1
Amyloid beta (A4) precursor-like protein 1.
      
 0.499
LOC101156270
Uncharacterized protein.
      
 0.499
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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