STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101175393Macrophage stimulating 1 receptor a. (1366 aa)    
Predicted Functional Partners:
LOC101168450
Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.933
hgf
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.933
grb2
Growth factor receptor-bound protein 2b.
    
 0.887
LOC101157091
PH domain-containing protein.
    
 0.879
gab1
GRB2-associated binding protein 1.
    
 0.879
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.852
LOC101163758
Uncharacterized protein.
    
 0.852
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase.
    
 0.852
LOC101158476
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.852
LOC101165394
GRB2 related adaptor protein 2a.
    
 0.836
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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