STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM11ADAM metallopeptidase domain 11. (776 aa)    
Predicted Functional Partners:
lgi3
Leucine-rich repeat LGI family, member 3.
     
 0.619
LOC101167242
Leucine-rich repeat LGI family, member 2a.
     
 0.583
LOC101171883
Leucine-rich repeat LGI family, member 2b.
     
 0.583
H2L2W9_ORYLA
Uncharacterized protein.
     
 0.570
adam23
ADAM metallopeptidase domain 23.
  
 
0.528
slit1
Slit homolog 1a (Drosophila).
     
 0.519
LOC101173732
Voltage-dependent anion channel 2.
      
 0.504
VDAC2
Voltage dependent anion channel 2.
      
 0.504
cables1
Cdk5 and Abl enzyme substrate 1.
      
 0.501
dlg3
Discs, large homolog 3 (Drosophila); Belongs to the MAGUK family.
   
 0.496
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.