Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lhbLuteinizing hormone, beta polypeptide. (146 aa)    
Predicted Functional Partners:
lhcgr
Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
   
 0.976
gnrh3
GnRH-associated peptide 3; Stimulates the secretion of gonadotropins. Belongs to the GnRH family.
      
 0.955
cga
Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family.
     
 0.936
gnrh2
GnRH-associated peptide 2; Stimulates the secretion of gonadotropins. Belongs to the GnRH family.
      
 0.905
kiss-2
12-RF amide peptide.
      
 0.877
chst8
Carbohydrate sulfotransferase.
     
  0.833
fshb
Cys_knot domain-containing protein.
   
 
 0.810
fshr
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
   
 0.795
nutf2
Nuclear transport factor 2.
   
 0.776
LOC110015983
NTF2 domain-containing protein.
   
 0.776
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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