Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sh2b3SH2B adaptor protein 3. (724 aa)    
Predicted Functional Partners:
LOC101168468
Tyrosine-protein kinase.
    
 0.728
tyk2
Tyrosine-protein kinase.
    
 0.728
LOC101175555
Tyrosine-protein kinase.
    
 0.728
LOC101157629
Tyrosine-protein kinase.
    
 0.728
jak1
Tyrosine-protein kinase.
    
 0.728
casz1
Castor zinc finger 1.
      
 0.690
ppm1f
Protein phosphatase, Mg2+/Mn2+ dependent, 1F.
      
 0.607
ccdc92
Coiled-coil domain containing 92.
      
 0.606
LOC101155816
Rho-GAP domain-containing protein.
      
 0.599
Kitlg
Kit ligand a.
     
 0.597
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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