Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arfgef3ARFGEF family member 3. (2276 aa)    
Predicted Functional Partners:
phb2
Prohibitin.
    
 
 0.966
orc5
Origin recognition complex, subunit 5.
      
 0.715
chmp7
Charged multivesicular body protein 7.
      
 0.698
ENSORLP00000043060
Uncharacterized protein.
      
 0.694
drg2
Developmentally regulated GTP binding protein 2.
      
 0.682
eapp
E2f-associated phosphoprotein.
      
 0.658
LOC101173369
Junction plakoglobin a.
      
 0.581
phb
Prohibitin.
    
 
 0.578
LOC101174444
Si:dkey-28o19.1.
      
 0.522
ctbs
Chitobiase, di-N-acetyl-; Belongs to the glycosyl hydrolase 18 family.
      
 0.464
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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