Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
htr75-hydroxytryptamine (serotonin) receptor 7a; Belongs to the G-protein coupled receptor 1 family. (452 aa)    
Predicted Functional Partners:
GNAS
Uncharacterized protein.
    
 0.925
LOC101166373
GNAS complex locus.
    
 0.925
cacng5
Calcium channel, voltage-dependent, gamma subunit 5a.
  
   
 0.743
GNAL
G protein subunit alpha L.
    
 0.738
LOC101155594
Si:ch73-60h1.1.
     
 0.656
PRKCB
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.574
rhobtb3
Si:dkey-6b12.5.
    
  0.542
LOC101158789
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.540
LOC101157835
Uncharacterized protein.
      
 0.509
fam126a
Family with sequence similarity 126 member A.
    
 
 0.509
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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