Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
H2LF66_ORYLASerine (or cysteine) peptidase inhibitor, clade H, member 2; Belongs to the serpin family. (415 aa)    
Predicted Functional Partners:
LOC101169766
Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family.
  
     0.526
ENSORLP00000040252
SERPIN domain-containing protein; Belongs to the serpin family.
  
     0.523
agt
Angiotensinogen; Belongs to the serpin family.
  
     0.516
ENSORLP00000045882
SERPIN domain-containing protein; Belongs to the serpin family.
  
     0.503
sec23a
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
     
 0.402
ENSORLP00000035411
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
     
 0.402
frem2
FRAS1 related extracellular matrix 2a.
     
 0.401
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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