Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
pak1ip1PAK1 interacting protein 1. (362 aa)    
Predicted Functional Partners:
rpf2
Ribosome production factor 2 homolog.
   
 
 0.981
rsl24d1
Ribosomal L24 domain containing 1.
   
 
 0.980
ebna1bp2
EBNA1 binding protein 2.
   
 
 0.967
wdr12
Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
  
 
 0.965
rsl1d1
Ribosomal L1 domain containing 1.
   
 
 0.960
mak16
Protein MAK16 homolog; Belongs to the MAK16 family.
   
 
 0.959
gtpbp4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.958
wdr74
WD repeat domain 74.
   
 
 0.955
nip7
60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.
   
 
 0.955
rrp15
Ribosomal RNA processing 15 homolog.
   
 
 0.954
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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