Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rfc3Replication factor C (activator 1) 3. (356 aa)    
Predicted Functional Partners:
rfc2
Replication factor C (activator 1) 2.
   
0.999
rfc4
Replication factor C (activator 1) 4.
   
0.999
rfc5
Replication factor C (activator 1) 5.
   
0.999
rfc1
Replication factor C subunit 1.
   
 0.999
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.998
dscc1
DNA replication and sister chromatid cohesion 1.
   
 0.997
chtf18
AAA domain-containing protein.
   
 0.992
rad17
RAD17 checkpoint clamp loader component.
   
 0.992
pola2
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
   
 0.979
chtf8
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae).
   
 0.971
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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