Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRSS23Serine protease 23. (408 aa)    
Predicted Functional Partners:
timp3
NTR domain-containing protein.
   
  
 0.665
adam22
ADAM metallopeptidase domain 22.
      
 0.654
fkbp10
Peptidylprolyl isomerase.
   
  
 0.651
atoh8
BHLH domain-containing protein.
      
 0.650
vgll3
Vestigial-like family member 3.
   
  
 0.647
prrx1
Paired related homeobox 1a.
   
  
 0.624
col6a1
Collagen, type VI, alpha 1.
   
  
 0.617
calu
Calumenin b.
      
 0.604
thbs1
Uncharacterized protein.
  
 
 0.580
ltbp2
Uncharacterized protein.
     
 0.574
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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