PRSS23 protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PRSS23

Serine protease 23. (408 aa)

Predicted Functional Partners:

adam22

0.602

mmp15

0.541

fkbp10

0.520

calu

0.510

vgll3

0.510

LOC105354657

0.508

atoh8

0.506

TGFB1I1

0.497

timp3

0.488

PTGIS

0.480

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC105354657	PRSS23	ENSORLP00000038073	ENSORLP00000004641	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	Serine protease 23.	0.508
LOC105354657	PTGIS	ENSORLP00000038073	ENSORLP00000000810	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	Prostaglandin I2 synthase; Belongs to the cytochrome P450 family.	0.605
LOC105354657	TGFB1I1	ENSORLP00000038073	ENSORLP00000026069	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	0.551
LOC105354657	atoh8	ENSORLP00000038073	ENSORLP00000037424	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	BHLH domain-containing protein.	0.615
LOC105354657	calu	ENSORLP00000038073	ENSORLP00000043773	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	Calumenin b.	0.570
LOC105354657	fkbp10	ENSORLP00000038073	ENSORLP00000041452	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	Peptidylprolyl isomerase.	0.633
LOC105354657	timp3	ENSORLP00000038073	ENSORLP00000011559	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	NTR domain-containing protein.	0.524
LOC105354657	vgll3	ENSORLP00000038073	ENSORLP00000045772	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	Vestigial-like family member 3.	0.619
PRSS23	LOC105354657	ENSORLP00000004641	ENSORLP00000038073	Serine protease 23.	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	0.508
PRSS23	PTGIS	ENSORLP00000004641	ENSORLP00000000810	Serine protease 23.	Prostaglandin I2 synthase; Belongs to the cytochrome P450 family.	0.480
PRSS23	TGFB1I1	ENSORLP00000004641	ENSORLP00000026069	Serine protease 23.	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.	0.497
PRSS23	adam22	ENSORLP00000004641	ENSORLP00000034262	Serine protease 23.	ADAM metallopeptidase domain 22.	0.602
PRSS23	atoh8	ENSORLP00000004641	ENSORLP00000037424	Serine protease 23.	BHLH domain-containing protein.	0.506
PRSS23	calu	ENSORLP00000004641	ENSORLP00000043773	Serine protease 23.	Calumenin b.	0.510
PRSS23	fkbp10	ENSORLP00000004641	ENSORLP00000041452	Serine protease 23.	Peptidylprolyl isomerase.	0.520
PRSS23	mmp15	ENSORLP00000004641	ENSORLP00000019295	Serine protease 23.	ZnMc domain-containing protein.	0.541
PRSS23	timp3	ENSORLP00000004641	ENSORLP00000011559	Serine protease 23.	NTR domain-containing protein.	0.488
PRSS23	vgll3	ENSORLP00000004641	ENSORLP00000045772	Serine protease 23.	Vestigial-like family member 3.	0.510
PTGIS	LOC105354657	ENSORLP00000000810	ENSORLP00000038073	Prostaglandin I2 synthase; Belongs to the cytochrome P450 family.	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	0.605
PTGIS	PRSS23	ENSORLP00000000810	ENSORLP00000004641	Prostaglandin I2 synthase; Belongs to the cytochrome P450 family.	Serine protease 23.	0.480