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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcnpPEST proteolytic signal containing nuclear protein. (171 aa)    
Predicted Functional Partners:
nppc
C-type natriuretic peptide 4; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
      
 0.690
dtymk
Deoxythymidylate kinase (thymidylate kinase).
      
 0.656
cct6a
Chaperonin containing TCP1, subunit 6A (zeta 1).
      
 0.624
med30
Mediator complex subunit 30.
      
 0.621
cgref1
Cell growth regulator with EF-hand domain 1.
      
 0.591
LOC101167120
Solute carrier family 25 member 39; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.580
caprin1
Cell cycle associated protein 1b.
      
 0.568
LOC101165381
Cell cycle associated protein 1a.
      
 0.568
cct8
Chaperonin containing TCP1, subunit 8 (theta).
      
 0.562
dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.
      
 0.559
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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