wwc3 protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

wwc3

WWC family member 3. (1150 aa)

Predicted Functional Partners:

xpnpep2

0.719

tmem9b

0.668

tmem9

0.668

lats2

0.643

lats1

0.642

exosc10

0.592

fbf1

0.567

map4k2

0.563

ostm1

0.550

H2M6E4_ORYLA

0.498

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2M6E4_ORYLA	exosc10	ENSORLP00000014038	ENSORLP00000006455	Uncharacterized protein.	Exosome component 10.	0.539
H2M6E4_ORYLA	fbf1	ENSORLP00000014038	ENSORLP00000015664	Uncharacterized protein.	Uncharacterized protein.	0.473
H2M6E4_ORYLA	wwc3	ENSORLP00000014038	ENSORLP00000004667	Uncharacterized protein.	WWC family member 3.	0.498
exosc10	H2M6E4_ORYLA	ENSORLP00000006455	ENSORLP00000014038	Exosome component 10.	Uncharacterized protein.	0.539
exosc10	fbf1	ENSORLP00000006455	ENSORLP00000015664	Exosome component 10.	Uncharacterized protein.	0.848
exosc10	wwc3	ENSORLP00000006455	ENSORLP00000004667	Exosome component 10.	WWC family member 3.	0.592
fbf1	H2M6E4_ORYLA	ENSORLP00000015664	ENSORLP00000014038	Uncharacterized protein.	Uncharacterized protein.	0.473
fbf1	exosc10	ENSORLP00000015664	ENSORLP00000006455	Uncharacterized protein.	Exosome component 10.	0.848
fbf1	wwc3	ENSORLP00000015664	ENSORLP00000004667	Uncharacterized protein.	WWC family member 3.	0.567
lats1	wwc3	ENSORLP00000022058	ENSORLP00000004667	Large tumor suppressor kinase 1.	WWC family member 3.	0.642
lats2	wwc3	ENSORLP00000034697	ENSORLP00000004667	Large tumor suppressor kinase 2.	WWC family member 3.	0.643
map4k2	wwc3	ENSORLP00000039584	ENSORLP00000004667	Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.	WWC family member 3.	0.563
ostm1	wwc3	ENSORLP00000016806	ENSORLP00000004667	Osteoclastogenesis associated transmembrane protein 1.	WWC family member 3.	0.550
tmem9	wwc3	ENSORLP00000037185	ENSORLP00000004667	Transmembrane protein 9.	WWC family member 3.	0.668
tmem9b	wwc3	ENSORLP00000008724	ENSORLP00000004667	TMEM9 domain family, member B.	WWC family member 3.	0.668
wwc3	H2M6E4_ORYLA	ENSORLP00000004667	ENSORLP00000014038	WWC family member 3.	Uncharacterized protein.	0.498
wwc3	exosc10	ENSORLP00000004667	ENSORLP00000006455	WWC family member 3.	Exosome component 10.	0.592
wwc3	fbf1	ENSORLP00000004667	ENSORLP00000015664	WWC family member 3.	Uncharacterized protein.	0.567
wwc3	lats1	ENSORLP00000004667	ENSORLP00000022058	WWC family member 3.	Large tumor suppressor kinase 1.	0.642
wwc3	lats2	ENSORLP00000004667	ENSORLP00000034697	WWC family member 3.	Large tumor suppressor kinase 2.	0.643