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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aste1XPG_I_2 domain-containing protein. (705 aa)    
Predicted Functional Partners:
fancm
Uncharacterized protein.
   
 0.653
pold2
Polymerase (DNA directed), delta 2, regulatory subunit.
    
 0.612
LOC100049345
Survival of motor neuron 1, telomeric.
    
 0.600
pold1
DNA polymerase.
   
 0.585
mus81
MUS81 structure-specific endonuclease subunit.
    
 0.583
Fam161a
FAM161 centrosomal protein A.
    
 
 0.562
tubgcp2
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
      
 0.559
taf1b
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B.
      
 0.559
snrpe
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.542
ddx20
DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.
   
 0.536
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.