Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101161926Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)    
Predicted Functional Partners:
bmp2
TGF_BETA_2 domain-containing protein.
    
 0.984
bmp4
Bone morphogenetic protein 4.
    
 0.984
LOC101163346
Bone morphogenetic protein 16.
    
 0.984
ACVR1B
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
   
0.980
INHBB
Inhibin subunit beta B.
   
 0.979
LOC100144359
TGF_BETA_2 domain-containing protein.
   
 0.979
mstn
TGF_BETA_2 domain-containing protein.
   
 0.979
ACVR1C
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
   
0.979
LOC101170230
Inhibin subunit beta Aa.
   
 0.979
inha
Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family.
    
 0.969
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.