Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mifMacrophage migration inhibitory factor. (115 aa)    
Predicted Functional Partners:
cops5
COP9 signalosome subunit 5.
    
 
 0.938
GOT1
Aspartate aminotransferase.
     
 0.927
got1
Aspartate aminotransferase.
     
 0.927
got2
Aspartate aminotransferase.
   
 
 0.922
cd74
CD74 molecule, major histocompatibility complex, class II invariant chain a.
   
 0.921
rps14
Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.
   
 0.921
tat
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
     
 0.919
LOC101157460
4-hydroxyphenylpyruvate dioxygenase.
     
 0.916
LOC101165831
4-hydroxyphenylpyruvate dioxygenase.
     
 0.916
LOC101163441
Amine oxidase.
     
  0.900
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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