s2012 protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

s2012

Uncharacterized protein. (922 aa)

Predicted Functional Partners:

smo

0.819

SPOP

0.791

spopl

0.791

Stk36

0.765

fbxw11

0.746

csnk1a1

0.723

ptch1

0.698

ptch2

0.698

gkap1

0.670

kif21b

0.670

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPOP	s2012	ENSORLP00000007031	ENSORLP00000004835	Uncharacterized protein.	Uncharacterized protein.	0.791
SPOP	spopl	ENSORLP00000007031	ENSORLP00000026834	Uncharacterized protein.	Speckle type BTB/POZ protein like b.	0.900
Stk36	csnk1a1	ENSORLP00000041898	ENSORLP00000025560	Protein kinase domain-containing protein.	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	0.611
Stk36	gkap1	ENSORLP00000041898	ENSORLP00000006448	Protein kinase domain-containing protein.	G kinase anchoring protein 1.	0.909
Stk36	kif21b	ENSORLP00000041898	ENSORLP00000020144	Protein kinase domain-containing protein.	Kinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.902
Stk36	ptch1	ENSORLP00000041898	ENSORLP00000005449	Protein kinase domain-containing protein.	Patched 1.	0.698
Stk36	ptch2	ENSORLP00000041898	ENSORLP00000044273	Protein kinase domain-containing protein.	Patched 2.	0.710
Stk36	s2012	ENSORLP00000041898	ENSORLP00000004835	Protein kinase domain-containing protein.	Uncharacterized protein.	0.765
Stk36	smo	ENSORLP00000041898	ENSORLP00000018001	Protein kinase domain-containing protein.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.947
csnk1a1	Stk36	ENSORLP00000025560	ENSORLP00000041898	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.611
csnk1a1	fbxw11	ENSORLP00000025560	ENSORLP00000005346	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	F-box and WD repeat domain containing 11a.	0.740
csnk1a1	gkap1	ENSORLP00000025560	ENSORLP00000006448	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	G kinase anchoring protein 1.	0.473
csnk1a1	kif21b	ENSORLP00000025560	ENSORLP00000020144	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	Kinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.473
csnk1a1	s2012	ENSORLP00000025560	ENSORLP00000004835	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.723
csnk1a1	smo	ENSORLP00000025560	ENSORLP00000018001	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.992
fbxw11	csnk1a1	ENSORLP00000005346	ENSORLP00000025560	F-box and WD repeat domain containing 11a.	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	0.740
fbxw11	s2012	ENSORLP00000005346	ENSORLP00000004835	F-box and WD repeat domain containing 11a.	Uncharacterized protein.	0.746
fbxw11	smo	ENSORLP00000005346	ENSORLP00000018001	F-box and WD repeat domain containing 11a.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.440
gkap1	Stk36	ENSORLP00000006448	ENSORLP00000041898	G kinase anchoring protein 1.	Protein kinase domain-containing protein.	0.909
gkap1	csnk1a1	ENSORLP00000006448	ENSORLP00000025560	G kinase anchoring protein 1.	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	0.473