Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101167140Doublecortin-like kinase 1a. (721 aa)    
Predicted Functional Partners:
dcx
Uncharacterized protein.
   
 
 0.925
Mc1r
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
    
 0.648
pot1
Protection of telomeres 1 homolog.
    
 
 0.644
LOC101170553
NME/NM23 family member 8; Belongs to the NDK family.
   
 0.579
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 
 0.548
LOC101170656
Si:ch211-194m7.4.
      
 0.533
LOC101175261
Pantothenate kinase 1a.
    
 
 0.502
LOC101161204
Pantothenate kinase 2.
    
 
 0.502
psmd3
Proteasome 26S subunit, non-ATPase 3.
   
 
 0.502
tert
Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
    
 
 0.498
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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