Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tlx3Homeobox domain-containing protein. (282 aa)    
Predicted Functional Partners:
npm3
Nucleophosmin/nucleoplasmin, 3.
      
 0.721
arx
Uncharacterized protein.
    
 0.632
TBX22
T-box transcription factor 22.
   
 
 0.535
aup1
AUP1 lipid droplet regulating VLDL assembly factor.
      
 0.504
fgf18
Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.
      
 0.493
prdm13
PR domain containing 13.
    
 
 0.469
LOC101170859
DEAQ box RNA-dependent ATPase 1.
   
  
 0.465
fbxw11
F-box and WD repeat domain containing 11a.
      
 0.440
loxl3
Lysyl oxidase-like 3b.
    
 0.431
lmo2
LIM domain only 2 (rhombotin-like 1).
    
 0.424
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.