STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tlx3Homeobox domain-containing protein. (282 aa)    
Predicted Functional Partners:
isl1
Uncharacterized protein.
   
 
 0.717
lhx1
LIM homeobox 1a.
    
 
 0.705
sim2
Uncharacterized protein.
   
  
 0.680
arx
Uncharacterized protein.
    
 
0.631
npm3
Nucleophosmin/nucleoplasmin, 3.
      
 0.592
loxl3
Lysyl oxidase-like 3b.
   
 
 0.508
fgf18
Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.
      
 0.502
fbxw11
F-box and WD repeat domain containing 11a.
      
 0.501
aup1
AUP1 lipid droplet regulating VLDL assembly factor.
      
 0.486
TBX22
T-box transcription factor 22.
   
 
 0.414
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.