close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sp4Sp4 transcription factor. (725 aa)    
Predicted Functional Partners:
tmem196
Uncharacterized protein.
      
 0.800
sp1
Sp1 transcription factor.
    
0.584
itgb8
Integrin beta; Belongs to the integrin beta chain family.
     
 0.559
abca2
ATP-binding cassette, sub-family A (ABC1), member 2.
    
 
 0.457
Ufc1
Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
      
 0.457
abcf3
ATP-binding cassette, sub-family F (GCN20), member 3.
    
 
 0.450
sumo1
Small ubiquitin-related modifier.
    
 0.446
slc25a40
Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.439
LOC101163434
ATP-binding cassette, sub-family H, member 1.
    
 
 0.413
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.