Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101163261SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (301 aa)    
Predicted Functional Partners:
LOC101165997
Cytochrome c oxidase assembly homolog 15 (yeast).
  
 0.983
smim20
Small integral membrane protein 20.
   
 
 0.965
COX14
Cytochrome c oxidase assembly factor COX14.
   
 0.956
cmc1
COX assembly mitochondrial protein.
   
 
 0.956
LOC101163528
Cytochrome C oxidase assembly factor 3a.
   
 0.955
LOC101161443
Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family.
  
 
 0.932
COX2
Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
  
 0.924
COX1
Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
  
 0.916
H2N085_ORYLA
SCO cytochrome c oxidase assembly protein 2.
  
 
 0.908
LOC101159951
Cytochrome c oxidase assembly homolog 11 (yeast).
  
 0.907
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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