Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
abcd3ATP-binding cassette, sub-family D (ALD), member 3a. (657 aa)    
Predicted Functional Partners:
pex19
Peroxisomal biogenesis factor 19.
    
 0.998
pex3
Peroxisomal biogenesis factor 3.
   
 0.953
LOC101173669
ATP-binding cassette, sub-family D (ALD), member 2.
   
 0.940
LOC101166202
ATP binding cassette subfamily D member 1.
   
 0.940
rad51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
   0.902
pex16
Peroxisomal membrane protein PEX16.
     
 0.896
Pex2
Peroxisomal biogenesis factor 2.
    
 0.879
pex13
Peroxisomal biogenesis factor 13.
   
 
 0.860
pex14
Peroxisomal biogenesis factor 14.
   
 0.845
pex12
Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.
   
 
 0.835
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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