Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC101164227Cyclin dependent kinase 17. (527 aa)    
Predicted Functional Partners:
cdc25b
Rhodanese domain-containing protein.
   
 0.775
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.766
mcm3
DNA helicase; Belongs to the MCM family.
   
 0.759
mcm4
DNA helicase; Belongs to the MCM family.
   
 0.744
ccna1
Cyclin A1; Belongs to the cyclin family.
   
 0.742
ccna2
Cyclin A2; Belongs to the cyclin family.
   
 0.742
orc2
Origin recognition complex, subunit 2.
   
 0.739
cdc7
Cell division cycle 7 homolog (S. cerevisiae); Belongs to the protein kinase superfamily.
   
 0.737
mad2l1
HORMA domain-containing protein.
   
 0.724
cdc23
CDC23 (cell division cycle 23, yeast, homolog).
    
 0.723
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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