| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dpyd | nudt15 | ENSORLP00000017096 | ENSORLP00000005127 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Nudix (nucleoside diphosphate linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family. | 0.802 |
| dpyd | tyms | ENSORLP00000017096 | ENSORLP00000013877 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Thymidylate synthetase. | 0.889 |
| fpgs | nadsyn1 | ENSORLP00000022891 | ENSORLP00000024320 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.407 |
| fpgs | nudt15 | ENSORLP00000022891 | ENSORLP00000005127 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Nudix (nucleoside diphosphate linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family. | 0.848 |
| fpgs | tyms | ENSORLP00000022891 | ENSORLP00000013877 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | Thymidylate synthetase. | 0.978 |
| nadsyn1 | fpgs | ENSORLP00000024320 | ENSORLP00000022891 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.407 |
| nadsyn1 | naprt | ENSORLP00000024320 | ENSORLP00000036059 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.861 |
| nadsyn1 | nudt15 | ENSORLP00000024320 | ENSORLP00000005127 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | Nudix (nucleoside diphosphate linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family. | 0.866 |
| naprt | nadsyn1 | ENSORLP00000036059 | ENSORLP00000024320 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.861 |
| naprt | nudt15 | ENSORLP00000036059 | ENSORLP00000005127 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nudix (nucleoside diphosphate linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family. | 0.846 |
| naprt | tyms | ENSORLP00000036059 | ENSORLP00000013877 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Thymidylate synthetase. | 0.443 |
| nudt14 | nudt15 | ENSORLP00000022194 | ENSORLP00000005127 | Nudix (nucleoside diphosphate linked moiety X)-type motif 14. | Nudix (nucleoside diphosphate linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family. | 0.918 |
| nudt14 | nudt18 | ENSORLP00000022194 | ENSORLP00000042512 | Nudix (nucleoside diphosphate linked moiety X)-type motif 14. | Nudix (nucleoside diphosphate linked moiety X)-type motif 18; Belongs to the Nudix hydrolase family. | 0.914 |
| nudt14 | nudt19 | ENSORLP00000022194 | ENSORLP00000014755 | Nudix (nucleoside diphosphate linked moiety X)-type motif 14. | Nudix (nucleoside diphosphate linked moiety X)-type motif 19. | 0.569 |
| nudt14 | nudt2 | ENSORLP00000022194 | ENSORLP00000010888 | Nudix (nucleoside diphosphate linked moiety X)-type motif 14. | Nudix (nucleoside diphosphate linked moiety X)-type motif 2. | 0.763 |
| nudt14 | nudt5 | ENSORLP00000022194 | ENSORLP00000025761 | Nudix (nucleoside diphosphate linked moiety X)-type motif 14. | Nudix (nucleoside diphosphate linked moiety X)-type motif 5; Belongs to the Nudix hydrolase family. | 0.901 |
| nudt15 | dpyd | ENSORLP00000005127 | ENSORLP00000017096 | Nudix (nucleoside diphosphate linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | 0.802 |
| nudt15 | fpgs | ENSORLP00000005127 | ENSORLP00000022891 | Nudix (nucleoside diphosphate linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.848 |
| nudt15 | nadsyn1 | ENSORLP00000005127 | ENSORLP00000024320 | Nudix (nucleoside diphosphate linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.866 |
| nudt15 | naprt | ENSORLP00000005127 | ENSORLP00000036059 | Nudix (nucleoside diphosphate linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.846 |