Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
hace1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (899 aa)    
Predicted Functional Partners:
rps27a
Ribosomal protein S27a.
    
 0.818
ubc
Ubiquitin B.
    
 0.817
trip12
Thyroid hormone receptor interactor 12.
   
 
 0.778
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.753
H2M970_ORYLA
Ubiquitin-like domain-containing protein.
    
 0.753
LOC101158291
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.736
fau
40S ribosomal protein S30.
    
 0.735
eprs1
Glutamyl-prolyl-tRNA synthetase.
   
   0.717
LOC101175372
RRM domain-containing protein.
    
 
 0.713
ALYREF
Aly/REF export factor.
    
 
 0.713
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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