STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Htr1a5-hydroxytryptamine receptor 1A. (422 aa)    
Predicted Functional Partners:
gng2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.818
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.818
LOC101168199
WD_REPEATS_REGION domain-containing protein.
    
  0.788
LOC101175500
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
  0.788
gnb4
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
    
  0.788
gnb5
Guanine nucleotide binding protein (G protein), beta 5a.
    
  0.773
gnb3
Guanine nucleotide binding protein (G protein), beta polypeptide 3a.
    
  0.773
LOC101156727
Guanine nucleotide binding protein (G protein), beta 5b.
    
  0.773
LOC105358374
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.
    
  0.765
gnao1
Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b.
    
  0.765
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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